METABOLISM OF ALLOXANIC ACID IN A SOIL MICROORGANISM
نویسندگان
چکیده
منابع مشابه
Metabolism of alloxanic acid in a soil microorganism.
Alloxan is a polyoxy-pyrimidine of unusual biological interest, being the agent of choice for producing experimental diabetes (Shaw-Dunn, Sheehan, and McLetchie, 1943). Despite the fact that it has been used extensively for many years, very little is known of its ultimate fate in mammals or other forms of life. It is exceedingly unstable at physiological pH values and is spontaneously converted...
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The occurrence in soil of a large group of bacteria which require vitamin B12 has been reported by Lochhead and Thexton (1952). Thirty cultures obtained from 534 isolates showed dependence upon vitamin B12 for growth. Lochhead and Burton (1954) grouped these 30 cultures into 10 types, based on morphological and physiological characteristics. A study of the nature of the vitamin B12 requirements...
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Since the discovery of alloxan diabetes in 1943 (l), several investigators have discussed the possibility that alloxan might be involved in some way in the pathogenesis of diabetes mellitus. Dunn et al. (1) considered this on the ground that alloxan was chemically related to uric acid. Lazarow (2) reviewed the possible relation of alloxan to diabetes and discussed the pro_ tective mechanism of ...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1961
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.81.5.755-761.1961